Meet Our Students

​洪愷浚

The student’s primary research centers on the development of an advanced biosensing platform designed for the sensitive detection of prostate cancer. This innovative system employs extended-gate field-effect transistors (EGFETs) that are functionalized with aptamers, enabling the specific recognition of prostate-specific antigen (PSA), a key biomarker for diagnosing prostate cancer.

Through the integration of nanomaterials and the application of electric double-layer modulation, the sensor achieves enhanced signal transduction, improves detection limits, and ensures consistent reproducibility. This research not only deepens the understanding of EGFET-based biosensors but also fosters the creation of rapid, non-invasive, and portable diagnostic tools for early-stage prostate cancer screening.

陳品柔

The student’s primary research is centered on the detection of acute myocardial infarction (AMI) using microRNA (miRNA) biomarkers. By leveraging extended-gate field-effect transistors (EGFETs) functionalized with specific aptamers, this system enables selective binding and sensitive detection of circulating miRNAs that are linked to cardiac injury, such as miR-133a and miR-1.

Employing electric double-layer modulation and signal amplification techniques, the biosensor achieves ultra-low detection limits and demonstrates reliable reproducibility. This research advances the use of nanotechnology-based EGFET platforms in cardiovascular diagnostics and aims to develop a rapid, minimally invasive, point-of-care testing tool for the early diagnosis of AMI.

張耀元

The student's primary research is centered on developing a biosensing platform for the detection of breast cancer. This system employs extended-gate field-effect transistors (EGFETs) that are functionalized with specific aptamers to target biomarkers such as HER2 and exosome-derived nucleic acids, which are closely linked to the progression of breast cancer.

By modifying nanomaterials and modulating the electric double layer, the sensor achieves heightened sensitivity, low detection limits, and excellent reproducibility. This research represents a significant advancement in non-invasive, rapid, and reliable diagnostic tools, aiming to enhance early breast cancer screening and support clinical decision-making.

李宜樺

The student’s primary research centers on the development of a biosensing platform designed to detect cardiac Troponin I (cTnI), the gold-standard biomarker for diagnosing acute myocardial infarction (AMI). This sensor employs extended-gate field-effect transistors (EGFETs) functionalized with aptamers, allowing for highly selective binding and sensitive measurement of Troponin I at clinically relevant concentrations.

By utilizing electric double-layer modulation and nanomaterial-assisted signal amplification, the platform significantly improves sensitivity, lowers detection limits, and ensures reliable reproducibility. This research contributes to the advancement of EGFET-based biosensors in cardiovascular disease diagnostics, aiming to create a rapid, non-invasive, point-of-care testing tool for the early detection of AMI.

吳宇恩

The student's primary research centers on the detection of chromium ions (Cr³⁺/Cr⁶⁺) utilizing an aptamer-functionalized extended-gate field-effect transistor (EGFET) platform. By employing highly specific aptamers for chromium ions, this biosensor achieves both selective recognition and sensitive detection, effectively addressing the pressing need to monitor heavy metal contamination in environmental and biomedical arenas.

With the use of electric double-layer modulation and nanomaterial-assisted signal enhancement, the platform exhibits improved sensitivity, low detection limits, and high reproducibility. This research underscores the potential of aptamer-based EGFET sensors as rapid, portable, and cost-effective tools for the detection of heavy metal ions and for monitoring environmental health.

​洪子皓

The student's primary research focuses on employing nanoparticle modification to regulate and optimize concentration-dependent interactions between aptamers and their targets. By coating sensing surfaces with nanoparticles, the system enhances the efficiency of aptamer immobilization, improves binding affinity, and adjusts the electric double-layer properties of the extended-gate field-effect transistor (EGFET).

This strategy facilitates more precise control over aptamer density and hybridization dynamics, resulting in enhanced sensitivity, reproducibility, and detection limits. The research not only advances our understanding of the mechanisms underlying aptamer-target coupling but also contributes to the development of high-performance biosensors for biomedical and environmental applications.